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Pharmacological treatments are reserved for specific circumstances and limited to licensed medications with demonstrated efficacy and safety profiles, such as orlistat or semaglutide (NICE TA875)

There is a suggestion that B12 supplementation may be useful for those who are already significantly deficient in B12, but doesn't do much for those who are not

Symptoms of vitamin B12 and folic acid deficiency anemia include: Shortness of breath Headache Indigestion Loss of appetite Heart palpitations Vision problems Feeling weak or tired Diarrhea Pain or redness of the tongue, sometimes with mouth sores Problems with memory, comprehension, and judgment (cognitive changes) Some of these symptoms may also occur in people who are deficient in vitamin B12 or folic acid but are not anemic

Reactions were performed with 0.001 mg/ml DNA substrate Poly(dI-dC), 1 M radiolabelled S-adenosyl-L-[methyl-3H] methionine (SAM) co-substrate, and recombinant human DNMT1 enzyme